Researchers have discovered that an FDA-approved drug acts on support cells in the central nervous system to encourage sensory neurons to regrow after injury.
Researchers can find signs of whether a person is on the way to developing the disease Lupus -- or is already ill. The revolutionary technique can be an important tool for diagnosing more autoimmune diseases.
Researchers may have an uncovered new answers on how to create safer opioids. Design a new opioid to bypass the part of brain that feels pleasure, but retain the analgesic properties, which make opioids one of the most effective pain relievers. Researchers looked at how opioids may have become so widely abused.
Researchers are examining neurons and hormones associated with eating too much. This study is another step in understanding the brain circuits involved in eating disorders.
A new study suggests multisystem inflammatory syndrome in children (MIS-C), a rare condition associated with COVID-19, is not caused by abnormal T cell response to COVID-19 virus as previously hypothesized.
New research examines psychological interventions for the treatment of chronic pain, including the gap between the evidence of the effectiveness of several psychological interventions and their availability and use in treatment.
The period after hospital discharge is a high-risk time for people who use illicit opioids such as heroin, according to new research. Fatal opioid overdoses are four times more likely in the first two days after hospital discharge than at other times, and people who use illicit drugs need extra support when being discharged from hospital.
'Think twice' campaign could reduce risk of UK opioid epidemic. A pilot campaign that urged GPs (family doctors) to 'think-twice' before putting a patient on opioid medicines was effective in reducing opioid prescribing in primary care, according to the findings of a major study. Although the reduction in the number of opioid prescriptions issued by individual GPs was small, when aggregated together they had a large effect.
Many people are confronted with chronic pain that can last for months or even years. How to best treat chronic pain? First, pain must be categorized for the right treatment to be prescribed. However, is that it is very challenging for patients to define their pain, its intensity or even its location using questionnaires. To overcome this difficulty, scientists have carried out a complete epigenomic analysis of patients, making it possible to find the epigenetic signatures specific to each pain category.
The study looked at patient outcomes from virtual care and remote automated monitoring (RAM) -- video calls with nurses and doctors, and self-monitoring of vital signs using wearable devices. Half of 905 post-surgery patients at nine sites in Hamilton, Kingston, London, Ottawa and Edmonton in Canada were randomized to use technology at home -- a cellular tablet and RAM equipment to measure their heart rate, blood pressure, oxygen saturation, respiration rate, body temperature and weight -- for 30 days after they left the hospital.
A study of chronic back pain patients finds that more than two-thirds of those who underwent a novel, 4-week psychological treatment were pain-free or nearly pain-free afterward. Those in the treatment group also saw brain regions involved in pain processing quiet. For many, the benefits lasted at least one year.
Physician-scientists developed a 12-week mind-body program that takes a new approach to chronic back pain. The team demonstrated that this intervention was highly beneficial for treating back pain when compared to standard care.
Complex autoimmune diseases affecting various organ systems remain one of the greatest medical challenges in spite of immense advances in treatment. In particular, the diffuse symptoms at the early stage of complex autoimmune diseases make it hard to diagnose the condition early on, which in turn delays treatment. A team of researchers has now demonstrated that treatment can be extremely effective if autoimmune diseases are treated as early as possible, even before the first clinical symptoms appear.
Can specific dietary guidelines help people living with bipolar disorders better manage their health? Clinical trial results showed that a diet designed to alter levels of specific fatty acids consumed by participants may help patients have less variability in their mood.
In a new single-arm study, researchers reported that radiation therapy as monotherapy is a safe and effective noninvasive treatment for oligometastatic renal cell carcinoma (RCC).
The number of people experiencing numbness, tingling and pain in their feet with no known cause has been increasing over the last two decades, according at a new study. Called small fiber neuropathy, the condition has different symptoms than large fiber neuropathy, which can cause weakness and balance issues. But in many cases people have both types of neuropathy.
Even low levels of physical therapy were associated with lower risk of chronic opioid use after total knee replacement. The team's analysis of over 67,000 patient records revealed that the longer a patient waits to start physical therapy, the greater the eventual odds of chronic opioid use.
The chair identifies sitting behavior associated with worsening low back pain, warning workers so they can get up and move around before the pain worsens.