Since the creation of 3D-printed (3DP) porous titanium scaffolds in 2016, the scientific community has been exploring ways to improve their ability to stimulate osteogenesis, or bone remodeling. A recent study revealed the osteogenic potential of Static Magnetic Field (SMF) treatment for human bone-derived mesenchymal stem cells (hBMSCs) using 3DP scaffolds in vitro and in vivo.
Researchers have become the first to describe a model of mitochondrial epilepsy which raises hope for better therapies for patients with this incapacitating condition.Despite the severity of this epilepsy, up to now there have been no animal models available to provide a mechanistic understanding of the condition. That is set to change though as researchers can now explain the important role that astrocytes play in seizure generation.
Researchers have discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors. Their findings reveal a novel binding site that will promote drug design of more efficient E1 inhibitors.
Children living in homes with all vinyl flooring or flame-retardant chemicals in the sofa have significantly higher concentrations of potentially harmful semi-volatile organic compounds (SVOCs) in their blood or urine than children from homes where these materials are not present, according to new research.
In conventional magnets, small magnetic constituents align with one another to create a strong magnetic field. By contrast, the newly-discovered type of magnet - the singlet-based magnet - has fields that pop in and out of existence, resulting in an unstable force. The idea for singlet-based magnets dates back to the 1960s, based on a [...]
Made from specially engineered infrared-sensitive yarn, which responds to changes in the temperature and humidity of a person’s skin by dynamically collapsing or expanding the structure of its fibers, the newly-developed textile shows great potential in the development of clothing systems capable of autonomously adapting to demanding environments. The human body absorbs and sheds much [...]
Following the discovery of the 19.2-mile (31 km) wide Hiawatha impact crater beneath the northwest margin of the Greenland Ice Sheet, Dr. Joe MacGregor of NASA’s Goddard Space Flight Center and colleagues explored satellite and aerogeophysical data in search of additional such craters and found a possible second impact crater that is 22.7 miles (36.5 [...]
An international team of researchers from the United States, Denmark and Sweden has pioneered a new approach that brings an oral formulation of insulin that can be swallowed rather than injected one step closer to the clinic. The scientists have developed an ingestible microneedle that can inject insulin into the stomach lining in a large [...]
Australia has the highest rate of mammal extinction in the world. Resettlement of indigenous communities resulted in the spread of invasive species, the absence of human-set fires, and a general cascade in the interconnected food web that led to the largest mammalian extinction event ever recorded. In this case, the absence of direct human activity on the landscape may be the cause of the extinctions, according to an anthropologist.
In two back-to-back symposia a cross-disciplinary cohort of scientists will present the first comprehensive investigations of how humans interacted with plant and animal species in different cultures worldwide through time.
A combination of two drugs -- one of them an immunotherapy agent -- could become a new standard, first-line treatment for patients with metastatic kidney cancer, results from a phase 3 clinical trial suggest.
Cooking, cleaning and other routine household activities generate significant levels of volatile and particulate chemicals inside the average home, leading to indoor air quality levels on par with a polluted major city.
While the polyester leisure suit was a 1970s mistake, polyester and other synthetic fibers like nylon are still around and are a major contributor to the microplastics load in the environment, according to a materials scientist, who suggests switching to biosynthetic fibers to solve this problem.
Just as conservators have developed methods to protect traditional artworks, computer scientists have now created means to safeguard computer- or time-based art by following the same preservation principles.
Researchers report that a new nuclear medicine tracer may allow better diagnosis of acute venous thromboembolism (VTE). Acute VTE is a disease that includes deep-vein thrombosis and its complication, pulmonary embolism, which can be fatal.
A team of scientists at the University of California San Diego has developed oral antivirulence vaccines powered by self-propelling micromotors that target the mucus layer of the intestine. Vaccines represent one of the most effective means of preventing infectious disease. They have saved millions of lives, but nobody likes getting a shot. That’s why researchers [...]