Evidence is steadily mounting that diet can influence lung health. The latest study demonstrates a link between eating fruit and veg and reduced COPD risk.
What is asthma and what is COPD? Who gets asthma and COPD, can other disorders cause similar symptoms, and what are the treatments for breathing disorders?
One of the largest studies to investigate whether Preserved Ratio Impaired Spirometry (PRISm), an understudied low lung function state, is an early predictor of co-morbidities has found it is strongly associated with an increased risk of death. The analysis evaluated results of lung spirometry tests in over 350,000 UK adults and followed them up over 12 years.
In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, flammation and lower diversity of microorganisms, compared to children with other illnesses who also have lung issues. They noted a clear divergence in these bacterial communities in toddlers, which is typically before progressive lung disease takes hold in patients with CF. Their findings could help providers target specific pathogens earlier, treat them and potentially prevent more severe lung disease.
Researchers have discovered that people with asthma and chronic obstructive pulmonary disease have a protein in their lungs that leaks a small molecule into their bloodstream that restricts their breathing instead of relaxing their airways. The findings will help clinicians diagnose and determine the severity of chronic lung diseases and make bronchodilators more effective.
Researchers working with primary care patients in China have discovered that a simple questionnaire and airflow measurement test could identify adults suffering with undiagnosed chronic obstructive pulmonary disease (COPD), a new study reveals.
Researchers have found that two populations of stem cells in the lung multiply during and after a viral respiratory infection, sometimes triggering a detrimental remodeling process that can cause persistent lung disease long after the virus has been cleared.
Increased air pollution in recent years has exacerbated health risks for people who suffer from pulmonary diseases and these dynamics underscore the importance of increasing the efficacy of drug delivery devices that administer active pharmaceutical ingredients to treat respiratory illnesses. Researchers describe developing a computational evaluation of drug delivery through both pressurized metered-dose inhalers and dry powder inhalers to determine how the process can be improved.
New research suggests that the airway cells of patients with chronic lung diseases are 'primed' for infection by the COVID-19 virus, resulting in more severe symptoms, poorer outcomes and a greater likelihood of death.
Inhibiting necroptosis, a form of cell death, could yield a new treatment approach for chronic obstructive pulmonary disease (COPD), an inflammatory lung condition also known as emphysema, new research shows. The study revealed elevated levels of necroptosis in patients with COPD. By inhibiting necroptosis activity in the lung tissue of COPD patients the researchers found a significant reduction in chronic airway inflammation and lung damage.
Researcher had previously discovered that the total mucin concentrations in the lungs are associated with COPD disease progression and could be used as diagnostic markers of chronic bronchitis, a hallmark condition for patients with COPD. They now report that one of these mucins, MUC5AC, is more closely and reliably associated with the development of COPD than is its brother, MUC5B.
Researchers have identified a panel of genes that are active in smokers and ex-smokers who experience faster loss of lung function over time. They believe these genes could be useful to predict which people are most at risk for smoking-related decline in lung function.
Pulmonary neuroendocrine cells, found in the human airway, are more varied than previously thought. Higher levels of certain types of pulmonary neuroendocrine cells are linked to sudden infant death syndrome and other breathing-related conditions.
In a series of experiments that began with amoebas -- single-celled organisms that extend podlike appendages to move around -- scientists say they have identified a genetic pathway that could be activated to help sweep out mucus from the lungs of people with chronic obstructive pulmonary disease a widespread lung ailment.
Scientists have implicated a type of immune cell in the development of chronic lung disease that sometimes is triggered following a respiratory viral infection. The evidence suggests that activation of this immune cell serves as an early switch that, when activated, drives progressive lung diseases, including asthma and chronic obstructive pulmonary disease (COPD).
A team of engineers has identified the 'violent' physical processes at work inside the lungs which cause wheezing, a condition which affects up to a quarter of the world's population.
A new study has uncovered a previously unknown role for exosomes in inflammatory respiratory diseases. The study has implications for finding new therapies. Exosomes are tiny compartments released from cells that carry different types of cargo, including inflammatory chemicals called cytokines that can drive lung disease.