The prevalence of obesity around the world has tripled over the past 40 years, and, along with that rise, dieting and attempts to lose weight also have soared. But according to a new article, when it comes to getting healthy and reducing mortality risk, increasing physical activity and improving fitness appear to be superior to weight loss. The authors say that employing a weight-neutral approach to the treatment of obesity-related health conditions also reduces the health risks associated with yo-yo dieting.
Being overweight or having obesity, weight that is higher than what is considered healthy for an individual's height, is a major risk factor for high blood pressure. A healthy diet, more physical activity and less sedentary time are recommended to reduce blood pressure for people who are overweight or have obesity; however, evidence of long-term weight loss and sustained blood pressure reductions from these lifestyle changes is limited. New weight-loss medications and bariatric surgery have shown benefits in both long-term weight loss and improved blood pressure, which can reduce the long-term, negative impact of high blood pressure on organ damage.
Weight loss after gestational diabetes can prevent the onset of type 2 diabetes. Yet finding the most effective way to lose weight and keep it off can be a challenge, especially for mothers with a new baby. Now, new research suggests that the popular 5:2 or intermittent fasting diet is just as effective as a conventional energy-restricting diet, enabling women greater choice and flexibility when it comes to weight loss.
Researchers analyzed ketogenic and calorically restricted diets in mice, revealing how those diets affect cancer cells and offering an explanation for why restricting calories may slow tumor growth.
Although there has been evidence of our species living in rainforest regions in Southeast Asia from at least 70,000 years ago, the poor preservation of organic material in these regions limits how much we know about their diet and ecological adaptations to these habitats. An international team of scientists has now applied a new method to investigate the diet of fossil humans: the analysis of stable zinc isotopes from tooth enamel. This method proves particularly helpful to learn whether prehistoric humans and animals were primarily eating meat or plants.
Scientists have known for a century that female animals become more active just as they are about to ovulate, a behavior that evolved to enhance their chances of mating when they are fertile.
In patients with COVID-19, a high body mass index (BMI) is associated with an increased risk of death and prolonged intensive care unit (ICU) stay, according to a new study.
Fasting levels of the 'hunger hormone' ghrelin rebound after weight loss and can help reduce belly fat and improve the body's sensitivity to insulin, according to a new study.
Migraines are a pain in the head and in the hip pocket, but newly discovered genetic causes could lead the way to new preventative drugs and therapies.
Missing out on the recommended seven or more hours of sleep per night could lead to more opportunities to make poorer snacking choices than those made by people who meet shut-eye guidelines, a new study suggests.
The prevalence of obesity around the world has tripled over the past 40 years, and, along with that rise, dieting and attempts to lose weight also have soared. But according to a new article, when it comes to getting healthy and reducing mortality risk, increasing physical activity and improving fitness appear to be superior to weight loss. The authors say that employing a weight-neutral approach to the treatment of obesity-related health conditions also reduces the health risks associated with yo-yo dieting.
Being overweight or having obesity, weight that is higher than what is considered healthy for an individual's height, is a major risk factor for high blood pressure. A healthy diet, more physical activity and less sedentary time are recommended to reduce blood pressure for people who are overweight or have obesity; however, evidence of long-term weight loss and sustained blood pressure reductions from these lifestyle changes is limited. New weight-loss medications and bariatric surgery have shown benefits in both long-term weight loss and improved blood pressure, which can reduce the long-term, negative impact of high blood pressure on organ damage.
Protein intake is known to be vital for maintaining brain function in older individuals. Now, using a mouse model of Alzheimer's disease, researchers have shown that the intake of a specific set of amino acids can inhibit the death of brain cells, protect the connections between them, and reduce inflammation, preserving brain function. Their research suggests that this amino acid combination called Amino LP7 can hinder the development of dementia, including Alzheimer's disease.
New findings show that fat cells control the systemic response to brain function, causing impairment in memory and cognition in mice. The activation of Na,K-ATPase oxidant amplification loop affects the expression of important protein markers in fat cells as well as in the hippocampus, which can worsen brain function and lead to neurodegeneration.
Scientists describe the first-in-human demonstration of a pathway that uses the sugar glucose, a component of table sugar and high fructose corn syrup, to signal the presence of calories, in addition to the well-studied sweet-taste receptor in taste buds.
Over the last few decades, scientists have discovered that long-term calorie restriction provides a wealth of benefits in animals. Researchers have largely assumed that reduced food intake drove these benefits by reprogramming metabolism. But a new study finds that reduced calorie intake alone is not enough; fasting is essential for mice to derive full benefit.
A study has revealed for the first time that the contraceptive pill can reduce the risk of type 2 diabetes by over a quarter in women with polycystic ovary syndrome (PCOS). The research findings also show that women with PCOS have twice the risk of developing type 2 diabetes or pre-diabetes (dysglycemia) -- highlighting the urgent need to find treatments to reduce this risk.
Consumption of ultra-processed foods has increased over the past two decades across nearly all segments of the U.S. population, according to a new study.
Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits. Researchers recently published a study showing that people who ate high-fiber products made from whole grain rye lost more body fat and overall weight than those who ate corresponding products made from refined wheat.