In a new study designed to better understand and combat these structures, scientists identified some of the key proteins in biofilms of the fungus Candida albicans that control both how they resist antifungal drugs and how they become dispersed throughout the body.
Researchers probing the gut -- 'the inner tube of life' -- have for the first time discovered specific factors in its workings that in the future may help improve treatment for patients facing gut damage or gastrointestinal disease.
When you have become immune to malaria after having contracted the disease, it seems that the body uses a more efficient protection than if you have been vaccinated against the deadly disease. The researchers believe the new findings may be used to improve existing malaria vaccines.
The most pristine parts of the Amazon rainforest devoid of direct human contact are being impacted by human-induced climate change, according to new research. New analyses of data collected over the past four decades show that not only has the number of sensitive resident birds throughout the Amazon rainforest declined, but the body size and wing length have changed for most studied species. These physical changes in the birds track increasingly hot and dry conditions in the dry season, from June to November.
A new study suggests that enlargement of stem cells contributes to age-related decline in function. The researchers found that blood stem cells, which are among the smallest cells in the body, lose their ability to perform their normal function -- replenishing the body's blood cells -- as they grow larger. When the cells were restored to their usual size, they behaved normally again.
Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published. The scientists have been investigating the use of gold nanoclusters - each made up of about 25 atoms of gold - to target and disrupt bacterial cells, making them more susceptible to standard antibiotic treatments.
Investigators have demonstrated temperature-sensitive regulation of actomyosin, a critical protein complex involved in neuronal development. By applying optically controlled heating, the team demonstrated that the protein drebrin E acts as a switch to inhibit actomyosin motility at physiological temperature, with inhibition occurring above a threshold drebrin E concentration. These findings have implications for understanding the role of temperature in embryo development and for the development of artificial nanoscale temperature sensors.
A new study shows how key features on the surface of HIV-infected cells help the disease evade detection by the immune system. It also shows how these features can be disabled.
New research shows that sea urchins, albeit having a limited and ancestral sensory system, can show a complex behaviour when escaping a predator. These marine invertebrates tend to move slowly and with unpredictable movements, but when they smell a predator, they escape following a ballistic motion -- straightforward, quick and directional -- to escape the threat.
A new study shows that there are species of marine animals such as fish, crustaceans and mollusks (for example, squid) that change their habitats and deepen an average of 55 meters across the climatic gradient of the Mediterranean (spanning a range of 6 degrees C).
Research suggested that autism spectrum disorder (ASD) may be at least partly caused by differences in the composition of the gut microbiota, based on the observation that certain types of microbes are more common in people with autism. But a new study suggests that the link may actually work the other way around: the diversity in species found in the guts of children with autism may be due to their restricted dietary preferences associated with autism, rather than the cause of their symptoms.
Investigators have found that an abnormal form of the tau protein is present in brain tissue from deceased patients who had amyotrophic lateral sclerosis (ALS). Cells that were grown in contact with deceased ALS patients' brain tissue that contained abnormal tau exhibited fragmentation of mitochondria and showed signs of oxidative stress. Reducing tau reversed these effects, lowering mitochondrial fragmentation and decreasing oxidative stress.
Researchers studying honey bees have found that colony size matters in determining how members of these 'superorganisms' make decisions in the face of dynamic survival conditions. Large, established colonies are less likely to take chances while smaller colonies working for stability are much more willing to take risks.
Tiny particles of gold could be the new weapon in the fight against bacterial antibiotic resistance, according to research just published. The scientists have been investigating the use of gold nanoclusters - each made up of about 25 atoms of gold - to target and disrupt bacterial cells, making them more susceptible to standard antibiotic treatments.
Investigators have demonstrated temperature-sensitive regulation of actomyosin, a critical protein complex involved in neuronal development. By applying optically controlled heating, the team demonstrated that the protein drebrin E acts as a switch to inhibit actomyosin motility at physiological temperature, with inhibition occurring above a threshold drebrin E concentration. These findings have implications for understanding the role of temperature in embryo development and for the development of artificial nanoscale temperature sensors.
Researchers discover further evidence of an evolutionary arms race within organisms -- and the mechanisms at play in this arms race -- to combat selfish genetic elements.
The flying reptiles known as pterosaurs are the closest relatives of dinosaurs and were the first vertebrates to evolve powered flight. However, many details of pterosaur flight anatomy and performance are still unclear. According to a new study pterosaurs evolved a muscular wing-body junction to reduce drag and improve flight performance.