The unfolded protein response plays a key role in how Middle East Respiratory Syndrome damages the lungs. MERS is much less common but much lethal than COVID-19, which is also caused by a coronavirus.
Unlike meerkats that take individual turns watching for predators while the rest forage, Barbary ground squirrels found off the coast of Africa stand sentry together -- a behavior called synchronous vigilance, according to a new study.
Researchers used transcriptomics (a type of gene sequencing) calibrated using information from the fossil record to create the first phylogenetic reconstruction of the insect order Odonata (dragonflies and damselflies), covering 105 species. This reconstruction of the evolutionary history allowed robust estimations of the species divergence time (or first appearance, around 200 million years ago) and the timing of evolutionary changes, such as the development of egg-laying organs.
A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes. Medical researchers have now developed a new drug-like molecule that can counteract the effects of mutated epigenetic regulators, which are known to drive certain types of cancer including lymphoma.
Scientists discover the genetics inside legumes that control the production of an oxygen-carrying molecule, crucial to the plant's close relationships with nitrogen-fixing bacteria. The finding offers the potential to give other plants the ability to produce ammonia from bacteria -- reducing the need for the fossil fuel-dependent and polluting practice of applying synthetic fertiliser to crops.
A new study shows how changes in light conditions have a significant influence on the growth and impact of harmful algae blooms. The bottom line: a warming climate looks good for the growth of toxic algae and may disrupt other organisms that are part of the food web -- whether they graze on this algae or are consumed by it.
While many animals have adapted to live with wildfires of the past -- which were smaller, more frequent and kept ecosystems in balance across the West -- it's unclear to scientists how animals are coping with today's unprecedented megafires. A team of researchers tracked a population of black-tailed deer before, during and after the 2018 Mendocino Complex Fire and found that most of the deer returned home within hours of the fire, while trees were still smoldering.
Cancer researchers show for the first time that cellular senescence, which occurs when aging cells stop dividing, is caused by irreversible damage to the genome rather than simply by telomere erosion.
Murky green algal blooms are more than a major eyesore; they reveal that a body of water could be unsafe for swimming or drinking. Currently, however, there isn't an effective warning system for impending blooms. Now, researchers report an indicator that changes color when exposed to rising levels of alkaline phosphatase -- an enzyme that forecasts phytoplankton's exponential growth. This change can be detected by the naked eye or a smartphone.
Seagrasses cover large swathes of shallow coastal seas, where they provide a vital habitat. They also remove large amounts of carbon dioxide (CO2) from the atmosphere and store it in the ecosystem. However, seagrasses need nutrients to thrive, particularly nitrogen. Up to now, researchers have assumed that the plants take up the nitrogen primarily from the surrounding seawater and sediment. However, in many of the regions where seagrasses are most successful there is little nitrogen to be found. Researchers now show that seagrass in the Mediterranean Sea lives in symbiosis with bacteria that reside in their roots and provide the nitrogen necessary for growth. Such symbioses were previously only known from land plants.
Spiny mice are known for their ability to heal severe skin wounds without so much as a scar. Now, researchers have discovered that they also can regenerate severely damaged internal organs that, in other mice, would lead to fatal organ failure. The findings in spiny mice are the first to show kidney regeneration in an adult mammal.
New research could help forensic teams understand whether people or animals were the victims of fatal lightning strikes, based solely upon an analysis of their skeletons.
Pinnipeds -- a group including seals, sea lions and walruses -- are relatively recently derived marine mammals that evolved from terrestrial carnivorans and reentered the marine environment. Their recent adaptations to an amphibious lifestyle make their evolutionary anatomy of particular interest.
Scientists may have made a giant leap in fighting the biggest threat to human health by using supercomputing to keep pace with the impressive ability of diseases to evolve. A new study has tackled the problem of antibiotic resistance by redesigning existing antibiotics to overcome bacterial resistance mechanisms.
New examinations of skeletons and animal embryos have allowed researchers to discover how mammals developed protruding, flexible noses. This study contributes to uncovering the origin of mammals' strong sense of smell and creates the potential for new animal models, like chickens or frogs, that are often used in lab experiments to investigate facial development disorders such as cleft palate.
Researchers discovered precisely how spiders build webs by using night vision and artificial intelligence to track and record every movement of all eight legs as spiders worked in the dark. Their creation of a web-building playbook or algorithm brings new understanding of how creatures with brains a fraction of the size of a human's are able to create structures of such elegance, complexity and geometric precision.
Synthetic biologists have developed eToeholds -- small versatile devices built into RNA that enable expression of a linked protein-encoding sequence only when a cell-specific or viral RNA is present. eToehold devices open up multiple opportunities for more targeted types of RNA therapy, in vitro cell and tissue engineering approaches, and the sensing of diverse biological threats in humans and other higher organisms.
Carbon occurs on the Earth in a variety of structures and forms. Elemental Carbon is usually formed under conditions of high pressure and temperature. Researchers have now, for the first time, identified microorganisms that produce elemental carbon.
Short growing seasons limited the possible size of hunter-gatherer societies by forcing people to rely on meat, according to a recent study. After looking at population size for the roughly 300 hunter-gatherer societies which existed until quite recently, the researchers found that many of these groups were much smaller than might have been expected from the local ecosystem productivity. In regions with short growing seasons, hunter-gatherer groups had smaller populations per square kilometre than groups who depended on abundant plant foods throughout the year.